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My partner worked in non-profits for years. Her advice is find local organizations (homeless shelters, local LGBT orgs, neighborhood revitalization orgs, ect.) that DO NOT have a national (central) office. Get to know their staff, their mission, and then make pledges to pay $X per month for the next X years. This is how they can best do the work they are passionate about to help people in need. Don’t put strings on the money and you are moving closer to mutual aid than tyranny.
Or less for less. I know a woman who is a manager of a dialysis clinic, as soon as she was making over 100k she started getting pushback from higher ups, having more oversight, and having her funds for extra services to patients / staff cut. It’s clear they want her out even though she has the lowest mortality in the region, because they don’t need more than beds filled (Medicaid pays) and legally required minimums to be met.