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The first successful transfection of designed mRNA packaged within a liposomal nanoparticle into a cell was published in 1989. “Naked” (or unprotected) lab-made mRNA was injected a year later into the muscle of mice.
But on the other hand, first human test was in 2001
There is a difference between well-written female characters that also happen to be strong vs hollow, soulless, undeveloped charachters whose only defining feature is being a “strong female character”.
See the difference beetween Ellen Ripley, Sarah Connor, Leia, Padme, Rita Vrataski, Gamora, Nebula, Naomi Nagata[1], and so on vs Galadriel (rings of power), Capitan Marvel, Ironhearth (MCU), She-hulk and whatever happened in Star Wars Acolyte (I could go on like this for a long time, but I think that you get what I mean already).
[1] I even included modern examples, to highlight that it’s not old good, new bad